“Can’t Hold Us” is a song by American hip hop duo Macklemore & Ryan Lewis from their debut studio album The Heist (2012). Featuring singer Ray Dalton, it was released as the third single from the album on August 16, 2011. The song also features additional vocals by actress Susannah Wetzel, who sings portions of the chorus alongside Dalton.
The song reached number one on the Billboard Hot 100, making it their second number-one hit in the United States. It is also their third consecutive number-one single in Australia.