“Me & U” is a song written by Ryan Leslie and recorded by American recording artist Cassie. It was released on April 25, 2006, as the lead single from her eponymous debut album, Cassie (2006). The song reached number three on the U.S. Billboard Hot 100 in 2006. It remained in the top forty for nearly five months. The single was certified platinum by the Recording Industry Association of America on December 14, 2006. It was also certified silver by the British Phonographic Industry.

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